doi: 10.1056/NEJMoa2108269
ZOA gains +19pp, Bang gains +21pp, Reign gains +20pp, PRIME gains +17pp
For one, the higher the dosage, the more at risk you are for the most common Wegovy side effects, which include nausea, constipation, and vomiting
What is typically included in a structured program A clear starting dose with gradual titration to reduce side effects Coaching on protein intake, hydration, and fiber for better fullness Strategies for nausea prevention and meal timing Progress tracking for weight, waist, energy, and appetite changes Follow up visits to adjust dose, address plateaus, and review labs This approach matters because appetite signals can change quickly, but body composition changes take time