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A clinician will typically start with a physical exam, and may order an ultrasound or blood tests to narrow down the cause

In laboratory settings, the activation of the Glucagon receptor is hypothesized to increase energy expenditure and improve mitochondrial function

There is a potential link between Melanotan use and skin cancer, which is kind of ironic as people take it as a "sun alternative." The catch is, while Melanotan stimulates melanin production, it can also darken existing moles and other pigmented lesions

Erastin can induce ferroptosis in human epidermal melanocytes, while NAC can protect melanocytes from ferroptosis in vitro [216]