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Yoon, K.-H

Kumar, S., & Tiwari, S

Early studies suggested that intestinal microbiota are altered in genetically obese mice with the metabolic syndrome and fatty livers, and these studies linked the abnormal microbiome with hepatic inflammatory signaling that promotes insulin resistance, hepatic steatosis, and nonalcoholic steatohepatitis.36-38 Subsequent work showed that the gut-liver axis has important bidirectional actions that affect health.39-42 The intestinal microbiota influence host susceptibility to obesity, hepatic steatosis, nonalcoholic steatohepatitis, liver fibrosis, and primary liver cancer

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