In the tirzepatide pivotal trials specifically, hair loss was reported in 4.9-5.3% of treatment groups compared to just 0.9% on placebo, yielding a relative risk of 5.67
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The most commonly reported side effects of retatrutide in clinical trials are gastrointestinal, including nausea, vomiting, diarrhoea, constipation, and decreased appetite, consistent with other GLP-1-based therapies