retatrutide peptide vs ozempic Comparing the Big 3, Semaglutide, Tirzepatide and : r/Mounjaro Is Stacking Retatrutide and Tirzepatide

In comparison, patients who used retatrutide (8 mg and 12 mg once weekly) lost 17.5% at 24 weeks and 24.2% of their body weight after 48 weeks in phase 2 clinical trials

The patches are said to be less effective at delivering GLP-1 agonist drugs, as they are large molecules

Lilly has signaled that detailed results will be presented at the American Diabetes Association Scientific Sessions in June 2026, with multiple additional Phase 3 readouts (TRIUMPH-2, TRIUMPH-3, and the cardiovascular outcomes trial) expected later in 2026 [1][10]

Medications Semaglutide, known by the brand name Wegovy, and liraglutide (Saxenda) have been specifically approved for weight loss in obesity, in combination with lifestyle changes