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Association between glucagon-like peptide-1 receptor agonists and the risk of glaucoma in individuals with type 2 diabetes
They reported it to be 43 amino-acids long and to have some molecular similarities to glucagon
Mechanistic studies indicate that GLP-1RAs suppress the perception of all basic taste modalities, probably through combined actions in the brainstem and vagal modulation, although paradoxical cases of sweet hypersensitivity have been documented in specific populations (162)
We hence intend to suggest that gut-produced native GLP-1 and peripherally administrated GLP- 1RA as therapeutic agent do not access the brain via BCB
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