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Before taking pramlintide, your doctor must know if you: Have impaired awareness of hypoglycaemia Are pregnant, planning to become pregnant or breastfeeding Are allergic to metacresol Have or have had gastroparesis Are taking antidepressants or antihistamines How to take pramlintide Pramlintide is taken as a subcutaneous injection, meaning that it is injected either by syringe or with a SymlinPen into the fatty tissue underneath the skin

People with longer histories of overeating may take 3-4 weeks to feel significant appetite changes, while others notice effects within days

An increase might have been observed in the tibial area bone mineral density (BMD, which is the ratio of BMC to area), but the total and vertebral area BMDs seem to have remained consistent

That sounds impossibly short for a compound that produces cognitive benefits lasting weeks beyond the final dose