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Circulation 147 , 6682 (2023)
S., Bourne Y., Tainer J
One study explored mechanistic associations between GLP-1 functioning and mood disorders in humans: a post-mortem investigation showed that, compared with healthy controls, patients who had been diagnosed with mood disorders had lower expression of the gene encoding for GLP-1R in the dorso-lateral prefrontal cortex and the hippocampus, whereas this association was not observed in the brain tissue of people with schizophrenia 176
At PDA Week 2025, Lorraine O'Shea from Eli Lilly's Kinsale team presented on plug flow reactor technology adapted for continuous peptide coupling reactions, describing how the approach eliminates the need for large-volume batch reactors while enabling scalable production
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