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Risk of hepatic events associated with use of sodium-glucose cotransporter-2 inhibitors versus glucagon-like peptide-1 receptor agonists, and thiazolidinediones among patients with metabolic dysfunction-associated steatotic liver disease

The 2023 international guideline supports metformin for adults with PCOS and BMI 25 kg/m for metabolic outcomes, but inositol is a reasonable alternative or adjunct for women who don't tolerate metformin or prefer a non-pharmaceutical option

More serious concerns include pancreatitis, gallbladder disease, dehydration, kidney injury, and allergic reactions

This makes it critical for individuals to evaluate whether they have the means and the discipline to save and invest HSA funds for the future