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Experts dont agree about why sleep deprivation has this effect

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Complementary metabolomic findings, including decreased carnitine derivatives associated with fatty acid oxidation, glycerolipids and monoacylglycerols, further support enhanced oxidative metabolism

In addition, curcumin has shown significant inhibitory effects on herpes simplex virus type 2 (HSV-2) and HIV-1 in vaginal epithelial cells and T lymphocytes, respectively (412)