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It is worth noting that F286 6.58 makes a greater contribution to ghrelins activity

In contrast, a second population of Dbh neurons (Grpr_Glu) that co-express the prolactin releasing hormone ( Prlh ) gene, previously linked to satiety signaling 43 , showed minimal response to LPS (four differentially expressed genes)

There is also interest in investigating the drugs impact on the gut microbiome and its interaction with dietary interventions, given the growing recognition of diet-microbiome interactions in IBS pathophysiology

Availability of data and materials All data generated or analysed during this study are included in this published article