Figure 2 Within the SOC level, gastrointestinal system disorders in overall GLP-1 RAs were overreported compared with the background frequency (ROR 1.46, PRR 1.33, IC 0.41, EBGM 1.33), which were further attributed to liraglutide (ROR 2.39, PRR 1.84, IC 0.88, EBGM 1.33), dulaglutide (ROR 1.39, PRR 1.28, IC 0.36, EBGM 1.25), and semaglutide (ROR 3.00, PRR 2.10, IC 1.07, EBGM 2.10), while exenatide (ROR 0.57, PRR 0.63, IC 0.68, EBGM 0.63) and lixisenatide (ROR 0.51, PRR 0.57, IC 0.81, EBGM 0.57) did not show the association with gastrointestinal AEs ( Table 2 )
Resveratrol improves oxidative stress and prevents the progression of periodontitis via the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense pathways in a rat periodontitis model
The Canadian Air Transport Security Authority (CATSA) provides clear guidelines for traveling with medications like semaglutide
Asayama K, Dobashi K, Hayashibe, Megata Y, Kato K