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Warady, B

Vitamin C helps stabilize and regenerate glutathione, while glutathione enhances the brightening effect of vitamin C

The disturbed proteostasis activates the unfolded protein response and protein degradation

Oxidative stress happens through several ways: Homocysteine goes through oxidation and auto-oxidation [18] Low folate reduces antioxidant enzyme activities, including superoxide dismutase and glutathione peroxidase [18] These changes create an environment that hurts cell function [18] Folate supplements can work as antioxidants by lowering homocysteine levels and boosting intraerythrocyte glutathione directly [19]