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Kim SY, Guevara JP, Kim KM, Choi HK, Heitjan DF, Albert DA

FIGURE 5 2.4.1 Vascular remodeling In DR, the RhoA/ROCK signaling pathway is activated by high glucose, which leads to endothelial dysfunction, breakdown of the blood-retinal barrier (BRB), and capillary leakage

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Side effects last approximately 5 weeks after discontinuing Ozempic or Wegovy, reflecting the medications clearance period