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Peripheral artery disease and Raynauds phenomenon PAD reduces blood flow to limbs, more commonly legs, but can affect armsleading to exertional pain, coolness, or numbness
In support to this theory, it has been demonstrated that GIP infusion increases the proliferation of neuronal progenitors in the dentate gyrus, while mice lacking GIP displayed deterioration in memorial tasks as a result of reduced neurogenesis [24]
However, many patients find the cost worthwhile for the long-term relief and the chance to avoid surgery or ongoing medication
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