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As epigenetic modifiers, STLs can modulate the p53 signaling pathway, suppress oncogenic signaling pathways, reduce the activation of major hepatocarcinogenesis-related oncogenes, and inhibit the epithelial-mesenchymal transition [110,111,112]

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Di Lorenzo A, Lin MI, Murata T, Landskroner-Eiger S, Schleicher M, Kothiya M, Iwakiri Y, Yu J, Huang PL, Sessa WC (2013) eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases