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This improvement has shown a decreased use of antihypertensive medications from baseline in the SURMOUNT-1 post hoc analysis [11] and an anticipated reduction in prescribed medication due to a 94% reduced risk of developing type 2 diabetes in adults with pre-diabetes and obesity or overweight [33]

The post says the product belongs in its original opaque container away from direct sunlight, and that every removal from refrigeration adds a period of room-temperature exposure

Gastrointestinal Adverse Effects As previously noted, the most common adverse of GLP-1 agonist drug use is nausea

Whatever schedule you choose, consistency is more important than the specific days