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One candidate mechanism underlying this neuroprotective effect lies in the ability of metformin to improve insulin sensitivity, reduce chronic inflammation, and exert direct effects on brain cells [24]

For chronic tendon, ligament, or soft-tissue problems, some protocols may extend to 8 weeks when there is clear benefit and good tolerance

That observation is now opening up the drugs to clinical trials for diseases that seem less obviously related to metabolic disorders, including Alzheimers, Parkinsons, depression and even cancer

As they move up, they start producing specific proteins that make your skin do its job well