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The role of OS in ALS pathology, whether as a primary cause of disease or a secondary consequence, is now well recognized and many preclinical and clinical studies have consistently demonstrated that the disease is characterized by high levels of OS markers able to induce cellular damage, impaired cell signalling, and finally cell death [25, 86]

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Summary Keywords assisted reproductive technology, capacitation, in vitro fertilization, implantation, live birth Citation Gmez-Elas MD, Luque GM, Oscoz-Susino N, Novero AG, Briski O, Ksparas I, Steeman TJ, Stival C, Lavolpe M, Julianelli V, Geller M, Attie M, Vassena R, Krapf D and Buffone MG (2025) Increased reproductive outcomes after optimized sperm preparation

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