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Although these tests require a large number of studies for reliable inference, formal statistical tests for the assessment of publication bias were not performed, as the results would be unreliable and potentially misleading
Oleoylethanolamide (OEA), an ethanolamide fatty acid synthesized in the body, can regulate glucose homeostasis and weight loss by stimulating GLP-1 secretion from intestinal L-cells and insulin secretion from -cells in a GPR119-dependent manner and by affecting the abundance of the bacterium Akkermansia muciniphila [146, 147]
For Rybelsus (oral semaglutide), diarrhea was reported in 7.5-8.5% of patients depending on the dose, compared to 4.1% with placebo
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