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Product Specifications Each vial in the Semaglutide Weight Loss Program with B-12 & Glycine is compounded for provider-prescribed use and includes the following formulation details: Per Vial Composition: Semaglutide + B-12 + Glycine Strength: 5 mg / 5 mg / 1 mg per mL Total Vial Size: 2 mL Form: Sterile injectable solution Total Active Content Per Vial: Semaglutide: 10 mg total per vial B-12: 10 mg total per vial Glycine: 2 mg total per vial Ordering Information: Maximum: Up to 3 vials per order Prescription required before fulfillment Compounded by a licensed pharmacy following provider approval All Wellness Medicines and Compounded Pharmacy Products require a Quick & Easy Medical Evaluation to Ensure the Medication is Appropriate for you

Further examining the change in gene expression revealed that an extensive number of these metabolic genes are increased in expression both at 24 h and 48 h (Extended Data Fig