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This regulation is particularly important in sperm maturation, where carnitine concentrations increase dramatically from the epididymal head (5 mM) to the tail (60 mM)

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[200] [78] [201] In locus coeruleus norepinephrine neurons, TAAR1-dependent RhoA signaling promotes EAAT3 internalization and subsequent glutamate reuptake inhibition

Figure 1 Considering the presence of the tumor, an open abdominal surgery was necessary for the treatment, thus requiring a conversion to an open procedure