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In the lacrimal glands of the aged mice, the Guangdong researchers found an increase in pro-fibrotic fibroblasts

The theoretical risk of over-activating the GH-IGF-1 axis, including acromegalic side effects and proliferative signaling, is additive

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intense neuronal activity can deplete intracellular ATP, leading to K_ATP channel opening and a consequent reduction in firing, serving as a dynamic, activity-dependent brake on excessive excitation in the auditory brainstem (de Siqueira et al., 2025)