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The cause of hepatic disease has been thought to be multifactorial in the setting of congestive hepatopathy from heart failure, malnutrition, previous or concomitant liver disease (i.e., infectious or autoimmune disease), and drug related liver injury, and possible liver ischemia from a mismatch between oxygen consumption and oxygen delivery to the liver (395-399)

In addition, NADPH generation via glutamine metabolism in cancer cells supports redox homeostasis by maintaining the cytosolic NADPH pool used to restore oxidized glutathione 29 (Fig

chloramphenicol), and concurrent iron or folic acid deficiency

The right choice depends on your specific health goals, lab results, and how your body responds to treatment