semaglutide discontinuation Could a weight loss drug also help the heart pump better? 🔬New research suggests semaglutide, a GLP-1 medication used to treat Type 2 diabetes and obesity, may improve heart function. It helps Effect of semaglutide 2.4 mg

Strength of recommendation: 1B Rationale: Atrial fibrillation is the most common arrhythmia worldwide and substantially increases the risk of stroke and thromboembolic events.130 Both DM and CKD are associated with an increased risk of developing atrial fibrillation as compared to the general population.130132 Furthermore, the presence of DM and/or CKD in patients with atrial fibrillation increases the risk of thromboembolic events,133136 as well as mortality and bleeding risks.136,137 The most common score used to estimate the thromboembolic risk and indication for oral anticoagulation is the CHA2DS2-VASc,130 and DM is one of the score items, therefore most patients with diabetes and CKD will indicate oral anticoagulation

Clinical trials including the STEP program demonstrated weight loss at all semaglutide doses above placebo, with greater loss at higher doses

Those who wish to improve anemia, prevent arteriosclerosis, and maintain overall health

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