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The cytotoxic effects of these copper compounds on HaCaT cells were observed to be concentration-dependent and time-dependent at concentrations 580 M and 5800 M

It's: What skin concern are you trying to address

An incorrect concentration throws off every subsequent measurement and makes your data unreliable

However, there was no difference in concentrations of two markers of myocardial injury (creatine kinase and troponin-I) or in the incidence of major adverse cardiac events one month after angioplasty between active treatment and placebo (45)