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[8] created the Summary-data-based Mendelian randomisation (SMR) method and the related instrumental heterogeneity test (HEIDI) method for assessing the robustness of SMR results, a great achievement that enriched the use of MR method further

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Oxyntomodulin is a biased agonist relative to GLP-1 4 , and forms distinct and more dynamic interactions with the GLP-1R, particularly with residues at the base of the peptide binding cavity that is located above the conserved central polar network that is important for receptor activation

Kessler also wrote that obesity is a metabolic disorder that causes the body to create too much fat tissue