the enzyme is also present in extracellular fluids as a glycoprotein.48 Most forms of GPx are tetrameric in structure but GPx4 which is often regarded as phospholipid hydroperoxide is a monomer and differ in substrate specificity
Tetzlaff MT, Messina JL, Stein JE, Xu X, Amaria RN, Blank CU, van de Wiel BA, Ferguson PM, Rawson RV, Ross MI, Spillane AJ, Gershenwald JE, Saw RPM, van Akkooi ACJ, van Houdt WJ, Mitchell TC, Menzies AM, Long GV, Wargo JA, Davies MA , Prieto VG, Taube JM, Scolyer RA
You cannot get this vitamin from plant-based products, but only from animal sources such as dairy products, eggs, fish, meat, and poultry
Another major symptom of vitamin E deficiency in humans is an increase in red blood cell fragility due to the increased level of erythrocyte membrane lipid peroxidation in the absence of tocopherols