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A comprehensive 2018 analysis by Pickart and Margolina revealed that GHK-Cu modulates the expression of approximately 4,000 human genes representing 31% of all genes analysed

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Another TKI, gefitinib (ZD1839, Iressa), which targets the epidermal growth factor receptor (EGFR), has been shown to restrict M.tb replication in both macrophages as well as in the lungs of M.tb -infected mice by promoting the host autophagy pathway through the inhibition of the p38 MAPK signaling pathway activated by EGFR [10]