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The study was registered at (NCT05446961) and was conducted in accordance with Good Clinical Practice Guidelines (GCP) and Brazilian National Health Council resolution 466/2021

[19] [20] Factors that increase bleeding risk include advanced age (65 years), history of bleeding, uncontrolled hypertension, labile INR (for warfarin users), concomitant antiplatelet therapy, excessive alcohol use, and certain comorbidities

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It's essential to monitor symptoms and consult a healthcare provider if diarrhea becomes debilitating