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IGF-1 stands for Insulin-like Growth Factor 1. It is a natural hormone produced in your liver that plays a critical role in childhood growth and continues to have anabolic (building) effects in adults

In addition, the leptin-receptor-expressing (LepR) neural activity in the dorsomedial hypothalamus (DMH), which sends GABAergic inhibitory inputs to ARC AgRP neurons, is also known to be rapidly increased by sensory detection, the taste of food, or food cues [48,53,54]