This includes monitoring IGF-1, IGFBP-3, and GH stimulation parameters, and designing a protocol that restores optimal GH axis function across all its effects: muscle, fat, sleep, skin, connective tissue, and metabolic health
For example, in cancer cells, the antioxidant system is upregulated through the activation of transcription factors like NRF2, resulting in the increased production of antioxidants such as glutathione (GSH) and superoxide dismutase (SOD) to neutralize excess reactive oxygen species and prevent toxicity (60)
Semaglutide and tirzepatide clinical trials demonstrate substantially larger reductions: participants lost 15% to 22% of body weight in the STEP trials over 68 weeks, with some reaching BMI reductions from obese to overweight categories
Mitochondria: the panacea to improve oocyte quality