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Notice that the two strongest cells REDEFINE 1 and SURMOUNT-1 are equally well-designed but structurally uncomparable: different sponsors, sites, durations, and comparator arms
Furthermore, the REWIND trial demonstrated a 12% reduction in major adverse cardiovascular events (MACE) ( p = 0.026), including among patients without established cardiovascular disease, alongside renoprotective effects evidenced by reductions in albuminuria [56]
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