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Effect of N-acetylcysteine administration on 30-day mortality in critically Ill patients with septic shock caused by carbapenem-resistant klebsiella pneumoniae and acinetobacter baumannii: a retrospective case-control study

Regarding treatment strategies, it is suggested that the marked decrease in GPx1 expression may be the major mechanism of tumor sensitization to anthracyclines [93] and that GPx1 can partially inhibit doxorubicin-induced cell death-related signaling in breast cancer by interfering with the activation of the sphingomyelin-ceramide pathway [85]