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(123) found plasma OS markers including malondialdehyde (MDA), carbonyl group, and dityrosine increased in obese patients (BMI, 3034.9 kg/m 2 ) compared to control subjects (BMI, 18.524.9 kg/m 2 )

Xanthine is further oxidized by xanthine dehydrogenase (XDH) to form urate [67]

We speculate that this reliance on CI-dependent NAD regeneration, together with the dynamic demands of lipid synthesis and storage, makes CI susceptible to circadian regulation in adipose tissue

Contact your doctor promptly if any side effects persist, worsen, or concern you, or if you experience any other concerning symptoms