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Additional experiments reported an apparent increase in collagen synthesis by fibroblasts, as well as improved hydration and elasticity in tested tissues

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A similar effect on TAG level has also been reported in 293HEK cells (62), while expression of desnutrin/ATGL in 3T3-L1 adipocytes has been shown to increase both glycerol and FA release (144)

Variables include: Age and baseline GHK levels Diet and overall nutrition Sleep quality and quantity Sun exposure and skin care habits Genetic factors affecting copper metabolism Concurrent health conditions Researchers who optimize supporting factors (sleep, nutrition, sun protection) typically report better outcomes than those relying solely on peptide administration