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Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance

A missed dose may: Disrupt the hormonal balance your body was adapting to Delay or alter your menstrual cycle May worsen cycle issues after weight loss or low calorie intake Its also worth noting that some women experience temporary cycle changes just from being on GLP-1 therapy, even if they havent missed a dose

Finan B, Yang B, Ottaway N et al (2012) Targeted estrogen delivery reverses the metabolic syndrome