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This article compares those pathways using FDA and manufacturer disclosures and platform terms as of December 26, 2025

The researchers found that after 52 weeks, Zepbound had led to an average reduction of 27.4 events per hour in people who were not on PAP machines, compared to a reduction of 4.8 events per hour for people on the placebo

For example, in the SUSTAIN 6 trial, which included over 3,000 participants, only a small number reported AFib

Clinicians should maintain a high index of suspicion for alternative diagnoses and investigate appropriately when patients report persistent or severe upper gastrointestinal symptoms