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While many people may meet the criteria for a GLP-1 weight loss clinical trial, some individuals may not be eligible due to safety concerns or study-specific exclusions

However, some cutting-edge technologies like PROTACs (proteolysis-targeting chimeras), RNA interference, clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-based genome editing, and artificial intelligence (AI)-based drug design, allow screening of therapeutics targeting almost all kinds of molecules, like proteins and epigenetic regulators

2006;27(4):921 to 930

doi: 10.3390/molecules24213813 Summary Keywords dietary fiber, burdock root, functional constipation, the aging, nutritional strategy Citation Mo L, Ma K, Li Y, Song J, Song Q and Wang L (2025) Dietary fiber from burdock root ameliorates functional constipation in aging rats by regulating intestinal motility