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People with these gene mutations may benefit not only from existing treatments but also from new medications designed to work specifically with these mutations

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Animal studies in diet-induced obesity models show tesofensine treatment produces selective reduction in adiposity with improvements in insulin sensitivity, reductions in plasma lipids, and decreased accumulation of abdominal and subcutaneous fat mass

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The development of GLP-1 receptor agonists Native GLP-1 is unsuitable itself as a therapeutic agent because of its short half-life in vivo

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