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51 Obstructive sleep apnoea In a one-year study of adults with moderate to severe obstructive sleep apnoea and obesity about half of whom were treated with positive airway pressure at baseline tirzepatide 10 or 15 mg once weekly resulted in a clinically meaningful reduction in the apnoeahypopnoea index compared with placebo

we went from thinking they would reverse it completely to worrying that TNFs actively cause exacerbations