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however, this methodology has inherent limitations.182 Furthermore, the guidelines do not differentiate recommendations based on the indication for GLP-1RAs use (eg, diabetes versus obesity) or the specific surgical procedure.74 In cases where patients report gastrointestinal symptoms on the day of surgery, postponement of the procedure is recommended.74 If patients do not adhere to the discontinuation recommendations, the Task Force advises implementing comprehensive gastric protective measures or considering the preoperative assessment of gastric volume via ultrasound

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Back Deacon, DF, Johnsen, AH, Holst, JJ (March 1995) 'Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo', Journal Clinical Endocrinology Metabolism , 80/3, 952-7