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In a meta-analysis of 16 RCTs of adults with diabetes and CKD (four of which included people with type 1 diabetes), spironolactone added to standard therapy was associated with a reduction in 24 h urinary albumin/protein excretion [66]

It is also hard to predict how people will think about these drugs over the long term, with a recent study by The New Consumer and Coefficient Capital showing that 46% of 1,810 consumers aware of GLP-1 weight loss drugs are extremely or very concerned about their long-term health impact, a figure that rises to 51% among users of such drugs (n-388)

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While treatment intent cannot be determined from claims data, GLP-1 use in newly diagnosed PMOS offers a useful window into how real-world care patterns are shifting in womens health