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They can dramatically damage skin cells and lead to premature ageing

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Indeed, based on the recently released EULAR (European League Against Rheumatism) points to consider on PsO to PsA transition, it is possible to identify a phase of psoriasis at higher risk for PsA that is typified by medium- to long-term risk factors (average of 712 years before PsA onset), including severe skin involvement, nail psoriasis, obesity and familial history for PsA, and a phase of subclinical PsA encompassing short-term risk factors (average of 13 years before PsA onset), including arthralgia and imaging evidence of synovio-entheseal inflammation (Fig

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