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In human fibroblast cultures, this has been shown to extend the "Hayflick limit" (the number of times a cell can divide) by over 10 passages

Many factors, including reactive oxygen species (ROS), are involved in AD pathogenesis by causing cellular damage and inflammation resulting in skin barrier dysfunction

2017;233(1):R15R42

The study of nuclear compartmentalization of GSH poses a significant methodological challenge and the findings were controversial over the last decade