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A cross-sectional study of 700 community-living, physically disabled women over the age of 65 found that vitamin B 12 -deficient women were twice as likely to be severely depressed as non-deficient women (97)

Injectable vitamin B12, which can treat significant deficiencies, may cause the following common side effects: More serious side effects of vitamin B12 injections can include: irregular heartbeat heart palpitations hives or a skin rash Vitamin B12 can cause very rare but serious allergic reactions, or anaphylaxis