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It increases heart rate and blood pressure, which limits its use in patients with hypertension or cardiovascular disease

Mol Syst Biol 17:e10280 Burley KH, Cuthbert BJ, Basu P, Newcombe J, Irimpan EM, Quechol R, Foik IP, Mobley DL, Beste DJV, Goulding CW (2021) Structural and molecular dynamics of Mycobacterium tuberculosis malic enzyme, a potential anti-TB drug target

He went on to say that many times over the years, patient families told him they didnt know where to go for care, and now any patient who walks through the door of Wellstar Childrens Hospital of Georgia will find physicians who are board-certified in many specialties