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Oxidative stress also activates the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 to regulate the expression of genes that control antioxidant, inflammatory and immune system responses, facilitating GSH activity

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BPC-157, a stable gastric pentadecapeptide, demonstrates broader systemic healing effects across multiple tissue types including tendons, muscles, and the gastrointestinal tract through angiogenic and growth factor pathways