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Fatty acid amide hydrolase (FAAH)/monoacylglycerol lipase (MAGL) dual inhibitors reduce endocannabinoid degradation, potentially providing neuroprotection and anti-inflammatory effects within the central nervous system

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The largest meta-analysis to date suggests GLP-1RAs may reduce major limb complications in people with type 2 diabetes and peripheral artery disease, although researchers say randomized trials are still needed to confirm a direct protective effect

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans