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Glutathione supports even skin tone by regulating melanin internally, it does not work as an instant or topical whitening agent

The main reason is receptor desensitization : continuous stimulation of the same receptor makes cells less responsive over time, so a planned off period lets the receptor resensitize

Access this article Similar content being viewed by others References Townsend DM, Tew KD, Tapiero H (2003) The importance of glutathione in human disease